| Date | Name | Role | Type | Shares | Value |
|---|---|---|---|---|---|
| Thu, 1 Oct 2026 | Heeson Lee | officer: EVP, Head of Incyte Intl | F-InKind | 463 | $54.24K |
| Wed, 30 Sep 2026 | BAKER BROS. ADVISORS LP | director, 10 percent owner | A-Award | 322 | $0 |
| Wed, 30 Sep 2026 | HARRIGAN EDMUND | director | A-Award | 206 | $25K |
| Wed, 30 Sep 2026 | Clancy Paul J | director | A-Award | 203 | $24.63K |
| Tue, 22 Sep 2026 | Gardner David H | officer: EVP, Chief Strategy Officer | F-InKind | 920 | $116.78K |
| Tue, 15 Sep 2026 | CAGNONI PABLO J | officer: President, Global Head of R&D | M-Exempt | 4,551 | $278.43K |
| Tue, 15 Sep 2026 | CAGNONI PABLO J |
| officer: President, Global Head of R&D |
| S-Sale |
| 9,233 |
| $1.11M |
| Tue, 15 Sep 2026 | CAGNONI PABLO J | officer: President, Global Head of R&D | S-Sale | 13,985 | $1.69M |
| Tue, 15 Sep 2026 | CAGNONI PABLO J | officer: President, Global Head of R&D | M-Exempt | 2,957 | $182.62K |
| Tue, 15 Sep 2026 | CAGNONI PABLO J | officer: President, Global Head of R&D | M-Exempt | 9,233 | $664.13K |
| Tue, 15 Sep 2026 | CAGNONI PABLO J | officer: President, Global Head of R&D | M-Exempt | 6,477 | $416.15K |
| Tue, 25 Aug 2026 | Basi Ramitpal K | officer: EVP, Human Resources | F-InKind | 504 | $65.38K |
| Wed, 19 Aug 2026 | CAGNONI PABLO J | officer: President, Global Head of R&D | S-Sale | 10,801 | $1.36M |
| Wed, 12 Aug 2026 | CAGNONI PABLO J | officer: President, Global Head of R&D | S-Sale | 10,803 | $1.3M |
| Wed, 12 Aug 2026 | CAGNONI PABLO J | officer: President, Global Head of R&D | S-Sale | 10,803 | $1.3M |
| Wed, 5 Aug 2026 | CAGNONI PABLO J | officer: President, Global Head of R&D | S-Sale | 10,640 | $1.31M |
| Wed, 5 Aug 2026 | Mayes Patrick A | officer: EVP & Chief Scientific Officer | M-Exempt | 2,207 | $234.98K |
| Wed, 5 Aug 2026 | CAGNONI PABLO J | officer: President, Global Head of R&D | S-Sale | 10,640 | $1.31M |
| Wed, 5 Aug 2026 | Mayes Patrick A | officer: EVP & Chief Scientific Officer | S-Sale | 2,207 | $273.65K |
| Wed, 5 Aug 2026 | Mayes Patrick A | officer: EVP & Chief Scientific Officer | S-Sale | 2,207 | $273.65K |
| Wed, 5 Aug 2026 | Mayes Patrick A | officer: EVP & Chief Scientific Officer | M-Exempt | 2,207 | $234.98K |
| Fri, 31 Jul 2026 | Mayes Patrick A | officer: EVP & Chief Scientific Officer | S-Sale | 2,864 | $341.96K |
| Fri, 31 Jul 2026 | Mayes Patrick A | officer: EVP & Chief Scientific Officer | S-Sale | 1,643 | $196.35K |
| Fri, 31 Jul 2026 | Mayes Patrick A | officer: EVP & Chief Scientific Officer | S-Sale | 1,642 | $196.02K |
| Fri, 31 Jul 2026 | Mayes Patrick A | officer: EVP & Chief Scientific Officer | S-Sale | 85 | $10.39K |
| Fri, 31 Jul 2026 | Mayes Patrick A | officer: EVP & Chief Scientific Officer | S-Sale | 326 | $39.67K |
| Fri, 31 Jul 2026 | Mayes Patrick A | officer: EVP & Chief Scientific Officer | M-Exempt | 2,284 | $146.75K |
| Fri, 31 Jul 2026 | Mayes Patrick A | officer: EVP & Chief Scientific Officer | M-Exempt | 2,918 | $178.52K |
| Fri, 31 Jul 2026 | Mayes Patrick A | officer: EVP & Chief Scientific Officer | S-Sale | 2,293 | $273.81K |
| Fri, 31 Jul 2026 | Mayes Patrick A | officer: EVP & Chief Scientific Officer | S-Sale | 4,695 | $560.54K |
| Fri, 31 Jul 2026 | CAGNONI PABLO J | officer: President, Global Head of R&D | S-Sale | 15,888 | $1.9M |
| Mon, 3 Aug 2026 | Mayes Patrick A | officer: EVP & Chief Scientific Officer | S-Sale | 6,055 | $729.2K |
| Fri, 31 Jul 2026 | Mayes Patrick A | officer: EVP & Chief Scientific Officer | M-Exempt | 3,148 | $216.02K |
| Fri, 31 Jul 2026 | Mayes Patrick A | officer: EVP & Chief Scientific Officer | M-Exempt | 2,072 | $149.04K |
| Fri, 31 Jul 2026 | Mayes Patrick A | officer: EVP & Chief Scientific Officer | M-Exempt | 9,459 | $683.6K |
| Fri, 31 Jul 2026 | Mayes Patrick A | officer: EVP & Chief Scientific Officer | M-Exempt | 1,643 | $132.26K |
| Fri, 31 Jul 2026 | Mayes Patrick A | officer: EVP & Chief Scientific Officer | M-Exempt | 3,023 | $251.51K |
| Fri, 31 Jul 2026 | Mayes Patrick A | officer: EVP & Chief Scientific Officer | M-Exempt | 2,623 | $219.23K |
| Fri, 31 Jul 2026 | Mayes Patrick A | officer: EVP & Chief Scientific Officer | M-Exempt | 1,642 | $139.59K |
| Fri, 31 Jul 2026 | Mayes Patrick A | officer: EVP & Chief Scientific Officer | M-Exempt | 2,293 | $207.65K |
| Fri, 31 Jul 2026 | Mayes Patrick A | officer: EVP & Chief Scientific Officer | M-Exempt | 85 | $9.05K |
| Fri, 31 Jul 2026 | Mayes Patrick A | officer: EVP & Chief Scientific Officer | M-Exempt | 2,864 | $222.45K |
| Fri, 31 Jul 2026 | Mayes Patrick A | officer: EVP & Chief Scientific Officer | M-Exempt | 326 | $34.37K |
| Fri, 31 Jul 2026 | Mayes Patrick A | officer: EVP & Chief Scientific Officer | S-Sale | 14,661 | $1.75M |
| Fri, 31 Jul 2026 | Mayes Patrick A | officer: EVP & Chief Scientific Officer | S-Sale | 5,332 | $636.75K |
| Fri, 31 Jul 2026 | Mayes Patrick A | officer: EVP & Chief Scientific Officer | M-Exempt | 2,709 | $167.31K |
| Fri, 31 Jul 2026 | Mayes Patrick A | officer: EVP & Chief Scientific Officer | S-Sale | 2,187 | $261.28K |
| Fri, 31 Jul 2026 | Mayes Patrick A | officer: EVP & Chief Scientific Officer | S-Sale | 6,171 | $737K |
| Mon, 3 Aug 2026 | Mayes Patrick A | officer: EVP & Chief Scientific Officer | M-Exempt | 6,055 | $638.38K |
| Thu, 16 Jul 2026 | CAGNONI PABLO J | officer: President, Global Head of R&D | A-Award | 13,403 | $0 |
| Holder | Shares | % out | Change |
|---|---|---|---|
| BAKER BROS. ADVISORS LP | 30,762,330 | 15.2% | +17,918 |
| BlackRock, Inc. | 18,032,718 | 8.9% | −945,480 |
| Dodge & Cox | 11,957,326 | 5.9% | −295,030 |
| VANGUARD CAPITAL MANAGEMENT LLC | 11,024,289 | 5.4% | +94,223 |
| STATE STREET CORP | 9,722,336 | 4.8% | +80,952 |
| VANGUARD PORTFOLIO MANAGEMENT LLC | 7,791,091 | 3.8% | +31,908 |
| AQR CAPITAL MANAGEMENT LLC | 5,320,901 | 2.6% | −487,029 |
| GEODE CAPITAL MANAGEMENT, LLC | 4,750,735 | 2.3% | +47,551 |
| Invesco Ltd. | 4,080,461 | 2.0% | +209,697 |
| WELLINGTON MANAGEMENT GROUP LLP | 3,575,521 | 1.8% | +309,385 |
| RENAISSANCE TECHNOLOGIES LLC | 3,512,132 | 1.7% | −139,400 |
| Renaissance Technologies | 3,512,132 | 1.7% | — |
| MORGAN STANLEY | 2,948,364 | 1.5% | +98,036 |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP |
| 2,744,958 |
| 1.4% |
| −85,841 |
| Robeco Institutional Asset Management B.V. | 2,441,735 | 1.2% | −72,648 |
