| Thu, 10 Sep 2026 | Ferguson Matthew | officer: CHIEF FINANCIAL OFFICER | M-Exempt | 12,500 | — |
| Thu, 10 Sep 2026 | Mills C Randal | director, officer: PRESIDENT AND CEO | F-InKind | 9,718 | $7.77K |
| Thu, 10 Sep 2026 | Mills C Randal | director, officer: PRESIDENT AND CEO | M-Exempt | 27,083 | — |
| Thu, 10 Sep 2026 | Williams Michelle LeRoux | officer: CHIEF SCIENTIFIC OFFICER | F-InKind | 4,269 | $3.42K |
| Thu, 10 Sep 2026 | Williams Michelle LeRoux | officer: CHIEF SCIENTIFIC OFFICER | M-Exempt | 12,500 | — |
| Thu, 10 Sep 2026 | Ferguson Matthew | officer: CHIEF FINANCIAL OFFICER | F-InKind | 4,486 | $3.59K |
| Sun, 21 Jun 2026 | Mills C Randal | director, officer: PRESIDENT AND CEO | M-Exempt | 22,473 | — |
| Sun, 21 Jun 2026 | Mills C Randal | director, officer: PRESIDENT AND CEO | F-InKind | 8,064 | $8.55K |
| Wed, 10 Jun 2026 | Ferguson Matthew | officer: CHIEF FINANCIAL OFFICER | M-Exempt | 12,500 | — |
| Wed, 10 Jun 2026 | Ferguson Matthew | officer: CHIEF FINANCIAL OFFICER | F-InKind | 4,485 | $4.66K |
| Wed, 10 Jun 2026 | Mills C Randal | director, officer: PRESIDENT AND CEO | F-InKind | 9,718 | $10.11K |
| Wed, 10 Jun 2026 | Mills C Randal | director, officer: PRESIDENT AND CEO | M-Exempt | 27,083 | — |
| Wed, 10 Jun 2026 | Williams Michelle LeRoux | officer: CHIEF SCIENTIFIC OFFICER | M-Exempt | 12,500 | — |
| Wed, 10 Jun 2026 | Williams Michelle LeRoux | officer: CHIEF SCIENTIFIC OFFICER | F-InKind | 4,269 | $4.44K |
| Mon, 1 Jun 2026 | HighCape Partners QP II, L.P. | 10 percent owner | J-Other | 50,000 | $0 |
| Mon, 1 Jun 2026 | HighCape Partners QP II, L.P. | 10 percent owner | G-Gift | 70,000 | $0 |
| Wed, 10 Dec 2025 | NEELS GUIDO J | director | M-Exempt | 6,250 | — |
| Tue, 10 Mar 2026 | Ferguson Matthew | officer: CHIEF FINANCIAL OFFICER | M-Exempt | 12,500 | — |
| Tue, 10 Mar 2026 | Mills C Randal | director, officer: PRESIDENT AND CEO | F-InKind | 11,100 | $12.1K |
| Tue, 10 Mar 2026 | Mills C Randal | director, officer: PRESIDENT AND CEO | M-Exempt | 27,084 | — |
| Tue, 10 Mar 2026 | Williams Michelle LeRoux | officer: CHIEF SCIENTIFIC OFFICER | M-Exempt | 12,500 | — |
| Tue, 10 Mar 2026 | Williams Michelle LeRoux | officer: CHIEF SCIENTIFIC OFFICER | F-InKind | 4,613 | $5.03K |
| Tue, 10 Mar 2026 | Ferguson Matthew | officer: CHIEF FINANCIAL OFFICER | F-InKind | 5,123 | $5.58K |
| Fri, 30 Jan 2026 | RAKIN KEVIN | director, 10 percent owner | P-Purchase | 70,000 | $74.2K |
| Fri, 30 Jan 2026 | NEELS GUIDO J | director | P-Purchase | 20,000 | $20.8K |
| Thu, 29 Jan 2026 | NEELS GUIDO J | director | P-Purchase | 15,000 | $15.9K |
| Wed, 28 Jan 2026 | NEELS GUIDO J | director | P-Purchase | 15,000 | $15.9K |
| Wed, 17 Dec 2025 | HighCape Partners GP II, LLC | 10 percent owner | P-Purchase | 50,000 | $26K |
| Thu, 11 Dec 2025 | HighCape Partners GP II, LLC | 10 percent owner | J-Other | 4,505,941 | — |
| Wed, 17 Dec 2025 | Ferguson Matthew | officer: CHIEF FINANCIAL OFFICER | P-Purchase | 60,000 | $31.8K |
| Wed, 17 Dec 2025 | Colpman David | director | P-Purchase | 12,500 | $6.38K |
| Wed, 17 Dec 2025 | Mills C Randal | director, officer: PRESIDENT AND CEO | P-Purchase | 3,000 | $1.53K |
| Wed, 17 Dec 2025 | Makes Brigid | director | P-Purchase | 25,000 | $13K |
| Thu, 11 Dec 2025 | RAKIN KEVIN | director, 10 percent owner | J-Other | 4,505,941 | — |
| Thu, 11 Dec 2025 | RAKIN KEVIN | director, 10 percent owner | J-Other | 4,372,497 | — |
| Wed, 10 Dec 2025 | Mills C Randal | director, officer: PRESIDENT AND CEO | F-InKind | 9,664 | $6.76K |
| Wed, 10 Dec 2025 | Ferguson Matthew | officer: CHIEF FINANCIAL OFFICER | M-Exempt | 12,500 | — |
| Wed, 10 Dec 2025 | Ferguson Matthew | officer: CHIEF FINANCIAL OFFICER | F-InKind | 4,461 | $3.12K |
| Wed, 10 Dec 2025 | Mills C Randal | director, officer: PRESIDENT AND CEO | M-Exempt | 27,083 | — |
| Wed, 10 Dec 2025 | Williams Michelle LeRoux | officer: CHIEF SCIENTIFIC OFFICER | M-Exempt | 12,500 | — |
| Wed, 10 Dec 2025 | Williams Michelle LeRoux | officer: CHIEF SCIENTIFIC OFFICER | F-InKind | 3,951 | $2.77K |
| Tue, 2 Dec 2025 | Ferguson Matthew | officer: CHIEF FINANCIAL OFFICER | P-Purchase | 5,500 | $3.69K |
| Mon, 1 Dec 2025 | Ferguson Matthew | officer: CHIEF FINANCIAL OFFICER | P-Purchase | 4,500 | $2.93K |
| Mon, 1 Dec 2025 | NEELS GUIDO J | director | M-Exempt | 6,250 | — |
| Mon, 24 Nov 2025 | Mills C Randal | director, officer: PRESIDENT AND CEO | P-Purchase | 5,000 | $3K |
| Mon, 17 Nov 2025 | Colpman David | director | P-Purchase | 15,500 | $11.47K |
| Thu, 13 Nov 2025 | Mills C Randal | director, officer: PRESIDENT AND CEO | P-Purchase | 3,500 | $2.66K |
| Thu, 13 Nov 2025 | Mills C Randal | director, officer: PRESIDENT AND CEO | P-Purchase | 5,000 | $3.7K |
