| Date | Name | Role | Type | Shares | Value |
|---|---|---|---|---|---|
| Thu, 11 Jun 2026 | June Carl Howard | director | A-Award | 16,568 | $0 |
| Thu, 11 Jun 2026 | Buetler Monika | director | A-Award | 17,751 | $0 |
| Thu, 11 Jun 2026 | Zuegel Martin | director, officer: Interim CEO | A-Award | 33,136 | $0 |
| Thu, 11 Jun 2026 | AGUIAR-LUCANDER RENEE | director | A-Award | 16,568 | $0 |
| Thu, 11 Jun 2026 | Twyman Roy Ervin | director | A-Award | 16,568 | $0 |
| Fri, 15 May 2026 | Pfeifer Andrea | director, officer: Chief Executive Officer | S-Sale | 10,000 | $27.9K |
| Wed, 15 Apr 2026 | Pfeifer Andrea | director, officer: Chief Executive Officer | P-Purchase | 10,000 | $31.4K |
| Wed, 15 Apr 2026 | Pfeifer Andrea | director, officer: Chief Executive Officer | S-Sale | 10,000 | $31.4K |
| Holder | Shares | % out | Change |
|---|---|---|---|
| BVF INC/IL | 19,822,436 | 19.5% | +0 |
| WELLS FARGO & COMPANY/MN | 1,004,041 | 1.0% | −243 |
| RENAISSANCE TECHNOLOGIES LLC | 840,127 | 0.8% | +215,760 |
| Renaissance Technologies | 840,127 | 0.8% | — |
| MILLENNIUM MANAGEMENT LLC | 773,594 | 0.8% | −19,063 |
| BlackRock, Inc. | 519,274 | 0.5% | −5,004 |
| DIMENSIONAL FUND ADVISORS LP | 340,082 | 0.3% | −50,083 |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | 232,953 | 0.2% | −172,705 |
| CITADEL ADVISORS LLC | 207,606 | 0.2% | −59,627 |
| MORGAN STANLEY | 131,815 | 0.1% | +42,562 |
| TWO SIGMA INVESTMENTS, LP | 102,825 | 0.1% | +63,734 |
| Qube Research & Technologies Ltd | 92,351 | 0.1% | — |
| UBS Group AG | 85,614 | 0.1% | −16,015 |
| GEODE CAPITAL MANAGEMENT, LLC | 61,854 |
| 0.1% |
| −1,747 |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 53,369 | 0.1% | −35,893 |
